Buy TRH Thyrotropin (Protirelin) 20 mg for Endocrine and CNS Research with Discreet Worldwide Shipping
TRH Thyrotropin, also known as Protirelin, is a synthetic tripeptide analog of the natural thyrotropin-releasing hormone. It plays a key role in stimulating thyroid-stimulating hormone (TSH) release and influencing central nervous system activity. Peptide Online Store provides high-purity TRH Thyrotropin (Protirelin) 20 mg, formulated for research and laboratory use only, delivered discreetly and securely worldwide.
What is TRH Thyrotropin (Protirelin)?
TRH (Protirelin) is a tripeptide hormone composed of pyroglutamyl-histidyl-proline amide. Originally isolated from the hypothalamus, it serves as the physiological regulator of TSH and prolactin secretion from the anterior pituitary. In research, Protirelin is used to study neuroendocrine signaling, thyroid regulation, and neuronal modulation.
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Synonyms: Thyrotropin-releasing hormone, Protirelin, TRH peptide
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CAS Number: 24305-27-9
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Molecular Formula: C₁₆H₂₂N₆O₄
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Molecular Weight: 362.38 g/mol
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Form: Lyophilized white powder
How Does TRH Thyrotropin (Protirelin) Work in the Body?
Protirelin binds to TRH receptors in the pituitary and hypothalamus, activating phospholipase C pathways and increasing intracellular calcium levels. This stimulation triggers the secretion of thyroid-stimulating hormone (TSH) and prolactin, modulating thyroid function and neuroendocrine balance.
Research also indicates TRH’s potential neuromodulatory roles in cognitive function, arousal, and neuroprotection, making it valuable for CNS and metabolic research models.
Key Benefits of TRH Thyrotropin (Protirelin) for Research
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Supports investigation of pituitary-thyroid axis regulation
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Useful in neuroendocrine signaling and neurotransmitter studies
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Valuable for examining CNS stimulation and neuroprotective mechanisms
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Enables modeling of thyroid and metabolic disorders
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Extensively cited in pharmacological and neurochemical research
Product Details and Purity
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Form: Lyophilized peptide, sterile-sealed vial
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Content: 20 mg TRH Thyrotropin (Protirelin)
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Purity: ≥ 99% (HPLC verified)
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Sequence: pGlu-His-Pro-NH₂
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Storage: –20 °C (long-term), 2–8 °C (short-term)
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Reconstitution: Use sterile distilled water or 0.9% NaCl for solution preparation
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Documentation: Certificate of Analysis (COA) and MS/HPLC data available upon request
Each batch undergoes rigorous analytical testing to confirm peptide identity, composition, and purity, ensuring reproducible research outcomes.
Dosage & Usage Guidelines
For laboratory investigations, TRH Thyrotropin is typically reconstituted in sterile water at the desired concentration. Dosage ranges vary depending on in-vitro or in-vivo experimental models. Researchers should handle and dilute using aseptic techniques.
Note: This compound is supplied strictly for scientific research use. It is not intended for human or veterinary consumption.
Safety, Side Effects & Precautions
While TRH Thyrotropin has been safely handled in research environments, standard peptide safety protocols must be followed:
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Use gloves, lab coat, and protective eyewear.
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Avoid inhalation or contact with skin.
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Dispose of materials per institutional biosafety guidelines.
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Store securely away from non-research areas.
Peptide Online Store complies with all regulations regarding research-only peptide distribution.
Quality Assurance & Testing
Each TRH Thyrotropin (Protirelin) 20 mg batch is:
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HPLC-verified for ≥99% purity
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Mass-spectrometry confirmed for sequence identity
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Tested for endotoxins and microbial contamination
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Produced in ISO 9001 and cGMP-compliant facilities
COA documents accompany all products to ensure transparency and reproducibility.
Commitment to Quality and Compliance
Peptide Online Store maintains strict compliance with global peptide manufacturing standards. All materials are ethically sourced, traceable, and independently verified. We are dedicated to scientific integrity, consistent quality control, and secure international shipping practices.
Potential Applications (For Research Use Only)
TRH Thyrotropin (Protirelin) 20 mg is utilized in studies related to:
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Hypothalamic-pituitary-thyroid (HPT) axis function
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Neuroendocrine communication and hormonal feedback
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Metabolic and thermoregulatory control
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Neuromodulation, behavior, and arousal research
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Endocrine pharmacology and CNS peptide mapping
(For laboratory research purposes only. Not approved for diagnostic or therapeutic use.)
Why Choose Peptide Online Store for TRH Thyrotropin (Protirelin)?
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Verified ≥99% purity and analytical COA
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Fast, discreet international shipping from certified facilities
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Competitive pricing and bulk order support
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Secure, encrypted online checkout
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Dedicated peptide specialists for product guidance
Our reputation is built on precision, reliability, and researcher trust across the global scientific community.
Shipping & Delivery Information
Orders are processed within 24 hours of confirmation.
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Domestic shipping: 2–4 business days
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International shipping: 5–10 business days
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All peptides are packaged in temperature-controlled, vacuum-sealed vials and shipped in discreet, insulated containers.
Tracking information is provided immediately upon dispatch.
How to Order Online
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Visit PeptideOnlineStore.com
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Search for “TRH Thyrotropin (Protirelin) 20 mg”
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Add to cart and proceed to secure checkout
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Select preferred shipping method
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Receive order confirmation and tracking via email
For institutional or bulk purchases, contact our research supply team for quotations and documentation support.
Frequently Asked Questions (FAQ)
Q: Is TRH Thyrotropin safe for human use?
A: No. It is for laboratory research only.
Q: Can I obtain a Certificate of Analysis?
A: Yes, COA and purity data are included with every batch.
Q: What is the shelf life?
A: Up to 24 months if stored properly at –20 °C.
Q: Do you ship internationally?
A: Yes. We offer discreet global shipping with tracking.
Q: Can Protirelin be used in animal studies?
A: Only under authorized research protocols and institutional guidelines.
Related Products to TRH Thyrotropin (Protirelin)
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GHRH (1-29) – for pituitary hormone release studies
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Somatostatin 14 – inhibitory peptide for endocrine research
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Buserelin Acetate – GnRH analog for reproductive axis exploration
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Final Thoughts
TRH Thyrotropin (Protirelin) 20 mg remains a cornerstone compound for exploring thyroid and neuroendocrine function. Researchers rely on Peptide Online Store for exceptional purity, transparent documentation, and dependable worldwide delivery.
Order today to advance your endocrine and neurochemical research with confidence.

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